NLRP3 Inflammasome Knockout Mice Are Protected against Ischemic but Not Cisplatin-Induced Acute Kidney Injury

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

Bettina Grasl Kraupp, Branislav Ruttkay-Nedecký, Helga Koudelka et al. · Hepatology · 1995 · 1.2K citations · Full text

Veterinary Medicine, Cell Biology, Molecular Biology +15

Update on Mechanisms of Ischemic Acute Kidney Injury

Prasad Devarajan · Journal of the American Society of Nephrology · 2006 · 1K citations

Medicine, Nephrology, Dialysis +15

Critical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1

Fayyaz S. Sutterwala, Yasunori Ogura, Marian Szczepanik et al. · Immunity · 2006 · 960 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

Martin Keller, Andreas Rüegg, Sabine Werner et al. · Cell · 2008 · 839 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

Shankar S. Iyer, Wilco P. Pulskens, Jeffrey J. Sadler et al. · Proceedings of the National Academy of Sciences · 2009 · 684 citations

Veterinary Medicine, Cell Biology, Immunology +17