Shankar S. Iyer

The Nalp3 inflammasome is essential for the development of silicosis

Suzanne L. Cassel, Stephanie C. Eisenbarth, Shankar S. Iyer et al. · Proceedings of the National Academy of Sciences · 2008 · 903 citations · Full text

Asthma, Nalp3 Inflammasome, Immunology +19

Mitochondrial Cardiolipin Is Required for Nlrp3 Inflammasome Activation

Shankar S. Iyer, Qiong He, John R. Janczy et al. · Immunity · 2013 · 863 citations · Full text

Inflammation, Mitochondrial Function, Cell Death +6

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

Shankar S. Iyer, Wilco P. Pulskens, Jeffrey J. Sadler et al. · Proceedings of the National Academy of Sciences · 2009 · 679 citations · Full text

Vitamin D Is Required for IFN-γ–Mediated Antimicrobial Activity of Human Macrophages

Mario Fabri, Steffen Stenger, Dong-Min Shin et al. · Science Translational Medicine · 2011 · 491 citations · Full text

Ifn-γ–mediated Antimicrobial Activity, Microbial Pathogens, Adaptive Immune System +23

Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

Anthony J. Covarrubias, Halil‐Ibrahim Aksoylar, Jiujiu Yu et al. · eLife · 2016 · 421 citations · Full text

Macrophage Activation, Immunology, Metabolic Remodeling +24