Effects of chronic acetyl-L-carnitine treatment on brain lipid hydroperoxide level and passive avoidance learning in senescence-accelerated mice

The aging process.

Denham Harman · Proceedings of the National Academy of Sciences · 1981 · 1.9K citations · Full text

Life Sciences, Immunology, Nutrition +17

The central cholinergic system studied by choline acetyltransferase immunohistochemistry in the cat

Hiroshi Kimura, Patrick L. McGeer, Jun Peng et al. · The Journal of Comparative Neurology · 1981 · 967 citations

Life Sciences, Anatomy, Neuroscience +16

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

John M. Carney, Pamela Starke‐Reed, Constance Oliver et al. · Proceedings of the National Academy of Sciences · 1991 · 725 citations

Life Sciences, Neurobiology, Neuroscience +15

Superoxide dismutase: correlation with life-span and specific metabolic rate in primate species.

J M Tolmasoff, Tetsuya Ono, R. G. Cutler · Proceedings of the National Academy of Sciences · 1980 · 381 citations · Full text

Life Sciences, Biochemistry, Biology +17

Senescence‐Accelerated Mouse (SAM): A Novel Murine Model of Accelerated Senescence

Toshio Takeda, Masanori Hosokawa, Keiichi Higuchi · Journal of the American Geriatrics Society · 1991 · 372 citations

Education, Cell Biology, Aging +9