Toshio Takeda

Fluorometric determination of amyloid fibrils in vitro using the fluorescent dye, thioflavine T

Hironobu Naiki, Keiichi Higuchi, Masanori Hosokawa et al. · Analytical Biochemistry · 1989 · 1.2K citations

Fluorometric Determination, Alzheimer's Disease, Engineering +10

Age-related changes in learning and memory in the senescence-accelerated mouse (SAM)

Masaomi Miyamoto, Yoshihiro Kiyota, Naoki Yamazaki et al. · Physiology & Behavior · 1986 · 379 citations

Age-related Changes, Developmental Biology, Aging +9

Senescence‐Accelerated Mouse (SAM): A Novel Murine Model of Accelerated Senescence

Toshio Takeda, Masanori Hosokawa, Keiichi Higuchi · Journal of the American Geriatrics Society · 1991 · 372 citations

Lifespan Extension, Developmental Biology, Aging +5

Induction of Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Mice Transgenic for HTLV-I

Yoichiro Iwakura, Mariko Tosu, Emi Yoshida et al. · Science · 1991 · 340 citations

Immunology, Pathology, Mice Transgenic +17

Age-related deterioration of ability of acquisition in memory and learning in senescence accelerated mouse: SAM-P/8 as an animal model of disturbances in recent memory

Hideo Yagi, Seika Katoh, Ichiro Akiguchi et al. · Brain Research · 1988 · 244 citations

Alzheimer's Disease, Developmental Biology, Aging +12