Characterization of the p53-rescue drug CP-31398 in vitro and in living cells

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

Yunje Cho, Svetlana S. Gorina, Philip D. Jeffrey et al. · Science · 1994 · 2.5K citations

Life Sciences, Molecular Biology, Oncology +16

Pharmacological Rescue of Mutant p53 Conformation and Function

Barbara A. Foster, Heather A. Coffey, Michael J. Morin et al. · Science · 1999 · 801 citations

Medicine, Oncology, Pharmacology +13

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

Alex N. Bullock, Julia Henckel, Alan R. Fersht · Oncogene · 2000 · 441 citations

Life Sciences, Molecular Biology, Oncology +16

Thermodynamic stability of wild-type and mutant p53 core domain

Alex N. Bullock, Julia Henckel, Brian S. DeDecker et al. · Proceedings of the National Academy of Sciences · 1997 · 418 citations

Life Sciences, Biochemistry, Molecular Biology +14

Solution structure of the tetrameric minimum transforming domain of p53

Weontae Lee, Timothy S. Harvey, Ya Yin et al. · Nature Structural & Molecular Biology · 1994 · 265 citations

Life Sciences, Biophysics, Molecular Biology +10