Increased frequency of circulating follicular helper T cells in lupus patients is associated with autoantibody production in a CD40L-dependent manner

The 1982 revised criteria for the classification of systemic lupus erythematosus

Eng M. Tan, Alan S. Cohen, James F. Fries et al. · Arthritis & Rheumatism · 1982 · 14.6K citations

Diagnosis, Pathology, Dermatology +19

Follicular B Helper T Cells Express Cxc Chemokine Receptor 5, Localize to B Cell Follicles, and Support Immunoglobulin Production

Dagmar Breitfeld, Lars Ohl, Elisabeth Kremmer et al. · The Journal of Experimental Medicine · 2000 · 1.4K citations · Full text

Lymphocyte Development, Adaptive Immune System, T-regulatory Cell +17

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

Carola G. Vinuesa, Matthew Cook, Constanza Angelucci et al. · Nature · 2005 · 855 citations

Immunogenetics, Autoimmune Disease, T-regulatory Cell +8

Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus

Nicholas Simpson, Paul A. Gatenby, Anastasia Wilson et al. · Arthritis & Rheumatism · 2009 · 666 citations

PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells

Kim L. Good‐Jacobson, Courtney G Szumilas, Lieping Chen et al. · Nature Immunology · 2010 · 652 citations · Full text

Cell Regulation, Cell Interaction, Immunology +6