Impacts of Cd(II) on the conformation and self-aggregation of Alzheimer's tau fragment corresponding to the third repeat of microtubule-binding domain

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Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease.

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Release of endogenous Zn2+ from brain tissue during activity

S.Y. Assaf, Shin‐Ho Chung · Nature · 1984 · 1.1K citations

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Metal-triggered Structural Transformations, Aggregation, and Fibrillation of Human α-Synuclein

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Life Sciences, Neurology, Neuroscience +16

Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif ( ³⁰⁶ VQIVYK ³¹¹ ) forming β structure

Martin von Bergen�, Peter Friedhoff, Jacek Biernat et al. · Proceedings of the National Academy of Sciences · 2000 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17