Concepedia

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: A microarray study

Nick Fletcher, David Wahlström, Rebecca Lundberg, Charlotte B. Nilsson, Kerstin Nilsson, Kenneth Stockling, Heike Hellmold, Helen Håkansson

Toxicology and Applied Pharmacology · 2005 · 184 citations · 113 references

DOI

Concepts

References

113

Identification of a Nuclear Receptor for Bile Acids

Makoto Makishima, Arthur Y. Okamoto, Joyce J. Repa et al. · Science · 1999 · 2.7K citations

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Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe et al. · Science · 1999 · 2.2K citations

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A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell · 2000 · 1.9K citations · Full text

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Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis

Christopher J. Sinal, Masahiro Tohkin, Masaaki Miyata et al. · Cell · 2000 · 1.8K citations · Full text

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Endogenous Bile Acids Are Ligands for the Nuclear Receptor FXR/BAR

Haibo Wang, Jasmine Chen, Kevin Hollister et al. · Molecular Cell · 1999 · 1.6K citations · Full text

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