Ex vivo activated OVA specific and non-specific CD4+CD25+ regulatory T cells exhibit comparable suppression to OVA mediated T cell responses

Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance

Jun Shimizu, Sayuri Yamazaki, Takeshi Takahashi et al. · Nature Immunology · 2002 · 1.7K citations

Autoimmune Disease, T-regulatory Cell, Immunology +8

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

Martha S. Jordan, Alina C. Boesteanu, Amy J. Reed et al. · Nature Immunology · 2001 · 1.6K citations

Signal Transduction, Autoimmune Disease, Lymphocyte Development +11

CD4+CD25+ Immunoregulatory T Cells

Rebecca S. McHugh, Matthew J. Whitters, Ciriaco A. Piccirillo et al. · Immunity · 2002 · 1.4K citations · Full text

Autoimmune Disease, T-regulatory Cell, Immunology +5

Compromised Function of Regulatory T Cells in Rheumatoid Arthritis and Reversal by Anti-TNFα Therapy

Michael R. Ehrenstein, J. Grimley Evans, Animesh Singh et al. · The Journal of Experimental Medicine · 2004 · 1.2K citations · Full text

Suppressor Effector Function of CD4+CD25+ Immunoregulatory T Cells Is Antigen Nonspecific

Angela M. Thornton, Ethan M. Shevach · The Journal of Immunology · 2000 · 1.2K citations