Rabbit CYP4B1 engineered for high-level expression in Escherichia coli: ligand stabilization and processing of the N-terminus and heme prosthetic group

Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.

Henry Barnes, Michael P. Arlotto, Michael R. Waterman · Proceedings of the National Academy of Sciences · 1991 · 563 citations

Life Sciences, Biochemistry, Molecular Biology +17

Expression of Modified Human Cytochrome P450 3A4 in Escherichia coli and Purification and Reconstitution of the Enzyme

Elizabeth M. J. Gillam, T. Baba, Bok‐Ryang Kim et al. · Archives of Biochemistry and Biophysics · 1993 · 347 citations

Life Sciences, Biochemistry, Molecular Biology +14

Formation of 20-Hydroxyeicosatetraenoic Acid, a Vasoactive and Natriuretic Eicosanoid, in Human Kidney

Jerome M. Lasker, W.Bill Chen, Imre Wolf et al. · Journal of Biological Chemistry · 2000 · 304 citations · Full text

Medicine, Nephrology, Drug Metabolism +16

Identification and Functional Characterization of a New CYP2C9 Variant (CYP2C9*5) Expressed among African Americans

Leslie J. Dickmann, Allan E. Rettie, M. Byron Kneller et al. · Molecular Pharmacology · 2001 · 250 citations

Life Sciences, Genetics, Molecular Genetics +11

Expression of Modified Human Cytochrome P450 1A2 in Escherichia coli: Stabilization, Purification, Spectral Characterization, and Catalytic Activities of the Enzyme

Punam Sandhu, Zhimou Guo, T. Baba et al. · Archives of Biochemistry and Biophysics · 1994 · 187 citations

Life Sciences, Biochemistry, Molecular Biology +17