Identification and Functional Characterization of a New CYP2C9 Variant (CYP2C9*5) Expressed among African Americans

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

Guruprasad P. Aithal, Christopher P. Day, Patrick Kesteven et al. · The Lancet · 1999 · 1.2K citations

Thrombosis, Medicine, Genetic Epidemiology +12

Substrate recognition sites in cytochrome P450 family 2 (CYP2) proteins inferred from comparative analyses of amino acid and coding nucleotide sequences.

Osamu Gotoh · Journal of Biological Chemistry · 1992 · 1.2K citations · Full text

Structural Bioinformatics, Biomolecular Structure Prediction, Signal Recognition +17

The role of the CFP2C9-Leu 359 allelic variant in the tolbutamide polymorphism

Theresa H. Sullivan-Klose, Burhan I. Ghanayem, Douglas A. Bell et al. · Pharmacogenetics · 1996 · 586 citations

Ethnicity as a variable in epidemiological research

Peter Senior, Raj Bhopal · BMJ · 1994 · 535 citations · Full text

Ethnicity, Fundamental Problems, Racial Health Equity +19

Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9

Allan E. Rettie, Larry C. Wienkers, Frank J. Gonzalez et al. · Pharmacogenetics · 1994 · 492 citations

Literary Theory, Comparative Literature, Biochemistry +12