Concepedia

Pyrin Activates the ASC Pyroptosome in Response to Engagement by Autoinflammatory PSTPIP1 Mutants

Je‐Wook Yu, Teresa Fernandes‐Alnemri, Pinaki Datta, Jianghong Wu, Christine A. Juliana, Leobaldo Solórzano, Margaret E. McCormick, Zhijia Zhang, Emad S. Alnemri

Molecular Cell · 2007 · 290 citations · 35 references

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35

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome

Hal M. Hoffman, James L. Mueller, David H. Broide et al. · Nature Genetics · 2001 · 1.7K citations

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A candidate gene for familial Mediterranean fever

Alain Bernot, Christian Clépet, Corinne Da Silva et al. · Nature Genetics · 1997 · 1.5K citations

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Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

The International FMF Consortium · Cell · 1997 · 1.5K citations · Full text

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The tripartite motif family identifies cell compartments

Alexandre Reymond, Germana Meroni, Anna Fantozzi et al. · The EMBO Journal · 2001 · 1.4K citations · Full text

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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

Teresa Fernandes‐Alnemri, Jiang Wu, Je‐Wook Yu et al. · Cell Death and Differentiation · 2007 · 1K citations · Full text

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