A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation

PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

Shaun Purcell, Benjamin M. Neale, Katherine EO Todd-Brown et al. · The American Journal of Human Genetics · 2007 · 36.1K citations · Full text

Life Sciences, Bioinformatics, Genetics +13

<i>IDH1</i>and<i>IDH2</i>Mutations in Gliomas

Hai Yan, D. Williams Parsons, Genglin Jin et al. · New England Journal of Medicine · 2009 · 5.9K citations · Full text

Medicine, Genetics, Oncology +16

Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

Houtan Noushmehr, Daniel J. Weisenberger, Kristin Diefes et al. · Cancer Cell · 2010 · 2.4K citations · Full text

Medicine, Molecular Genetics, Oncology +14

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

Şevin Turcan, Daniel Rohle, Anuj Goenka et al. · Nature · 2012 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +14

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Chao Lü, Patrick S. Ward, Gurpreet S. Kapoor et al. · Nature · 2012 · 2K citations

Life Sciences, Genetics, Molecular Biology +14