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Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists

Mahmood Ahmed, Michael A. Briggs, Steven M. Bromidge, Tania Buck, Lorraine Campbell, Nigel Deeks, Ashley E. Garner, Laurie Gordon, Dieter Hamprecht, Vicky Holland,

Bioorganic & Medicinal Chemistry Letters · 2005 · 47 citations · 7 references

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7

The reaction of vinyl grignard reagents with 2-substituted nitroarenes: A new approach to the synthesis of 7-substituted indoles

Giuseppe Bartoli, Gianni Palmieri, Marcella Bosco et al. · Tetrahedron Letters · 1989 · 327 citations

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5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation—an effect sensitive to NMDA receptor antagonism

Madeleine V. King, Andrew J. Sleight, Marie L. Woolley et al. · Neuropharmacology · 2004 · 194 citations

, , +17

5-Chloro-<i>N</i>-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046):  A Potent, Selective, and Orally Bioavailable 5-HT<sub>6</sub> Receptor Antagonist

Steven M. Bromidge, Anthony M. Brown, Stephen E. Clarke et al. · Journal of Medicinal Chemistry · 1999 · 170 citations · Full text

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5-HT 6 receptor antagonists enhance retention of a water maze task in the rat

D F Rogers, J.J. Hagan · Psychopharmacology · 2001 · 152 citations

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Mechanistic studies on the reaction of nitro- and nitrosoarenes with vinyl Grignard reagents

Marcella Bosco, Renato Dalpozzo, Giuseppe Bartoli et al. · Journal of the Chemical Society Perkin Transactions 2 · 1991 · 68 citations

, , +9