Concepedia

Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis

Basil Hartzoulakis, Sharon Rossiter, Herpreet Gill, B.P. O'Hara, Emily Steinke, Paul J. Gane, Ramón Hurtado‐Guerrero, James Leiper, Patrick Vallance, Judith Murray Rust,

Bioorganic & Medicinal Chemistry Letters · 2007 · 28 citations · 20 references

DOI

Concepts

References

20

Hierarchical Grouping to Optimize an Objective Function

Joe H. Ward · Journal of the American Statistical Association · 1963 · 19.2K citations

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Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 8.1K citations

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Simple Selection Criteria for Drug-like Chemical Matter

Ingo Muegge, Sarah L. Heald, David R. Brittelli · Journal of Medicinal Chemistry · 2001 · 1.3K citations

, , +11

Computational methods for the prediction of ‘drug-likeness’

David E. Clark, Stephen D. Pickett · Drug Discovery Today · 2000 · 573 citations

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Disruption of methylarginine metabolism impairs vascular homeostasis

James Leiper, Manasi Nandi, Belén Torondel et al. · Nature Medicine · 2007 · 403 citations

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