James Leiper

Asymmetric Dimethylarginine Causes Hypertension and Cardiac Dysfunction in Humans and Is Actively Metabolized by Dimethylarginine Dimethylaminohydrolase

Vinod Achan, Michael Broadhead, Mohammed Malaki et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2003 · 595 citations

Medicine, Cardiology, Pharmacology +14

Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases

James Leiper, Ann Chubb, Raymond J. MacAllister et al. · Biochemical Journal · 1999 · 469 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Disruption of methylarginine metabolism impairs vascular homeostasis

James Leiper, Manasi Nandi, Belén Torondel et al. · Nature Medicine · 2007 · 403 citations

Life Sciences, Biochemistry, Molecular Biology +10

<i>S</i> -nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: Further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase

James Leiper, Judith Murray‐Rust, Neil Q. McDonald et al. · Proceedings of the National Academy of Sciences · 2002 · 292 citations

Life Sciences, Biochemistry, Molecular Biology +16

Unexpected Effect of Proton Pump Inhibitors

Yohannes T. Ghebremariam, Paea LePendu, Jerry C. Lee et al. · Circulation · 2013 · 254 citations

Medicine, Cardiology, Pharmacology +16