Concepedia

Formal total synthesis of camptothecin via ring-closing metathesis strategy

Subhash P. Chavan, K. Pasupathy, M.S. Venkatraman, Ramesh R. Kale

Tetrahedron Letters · 2004 · 35 citations · 36 references

DOI

Concepts

References

36

The Development of L<sub>2</sub>X<sub>2</sub>RuCHR Olefin Metathesis Catalysts:  An Organometallic Success Story

Tina M. Trnka, Robert H. Grubbs · Accounts of Chemical Research · 2000 · 3.5K citations

, , +16

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

, , +15

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata<sup>1,2</sup>

Monroe E. Wall, Mansukh C. Wani, Clarence Cook et al. · Journal of the American Chemical Society · 1966 · 2.2K citations

, , +8

Recent advances in olefin metathesis and its application in organic synthesis

Robert H. Grubbs, Sukbok Chang · Tetrahedron · 1998 · 2.1K citations

, , +8

The Alkaloids, Chemistry and Pharmacology

European Journal of Medicinal Chemistry · 1992 · 916 citations

, , +10