Concepedia

Synthesis of highly potent RXR-specific retinoids: The use of a cyclopropyl group as a double bond isostere

Vidyasagar Vuligonda, Yuan Lin, Roshantha A.S. Chandraratna

Bioorganic & Medicinal Chemistry Letters · 1996 · 43 citations · 28 references

DOI

Concepts

References

28

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Identification of a receptor for the morphogen retinoic acid

Vincent Giguère, Estelita S. Ong, Prudimar Segui et al. · Nature · 1987 · 2K citations

, , +12

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

Richard A. Heyman, David J. Mangelsdorf, Jacqueline A. Dyck et al. · Cell · 1992 · 1.8K citations

, , +11

Oxidation of long-chain and related alcohols to carbonyls by dimethyl sulfoxide "activated" by oxalyl chloride

Anthony J. Mancuso, Shui‐Lung Huang, Daniel Swern · The Journal of Organic Chemistry · 1978 · 1.6K citations

, , +5

Nuclear receptor that identifies a novel retinoic acid response pathway

David J. Mangelsdorf, Estelita S. Ong, Jacqueline A. Dyck et al. · Nature · 1990 · 1.5K citations

, , +14