Bioscience Biotechnology and Biochemistry · 2004 · 40 citations · 9 references
MedicineNutritionNutritional SciencesAnimal NutritionBone MetabolismMineral MetabolismBone HealthBone Metabolism DisordersEssential Fatty AcidsFracture PreventionMetabolic Bone DiseaseOsteoporosisBone Mineral DensityBone Mineral Density DeclineEicosapentaenoic AcidFatty Acid Effects On Calcium AbsorptionFish Oil SupplementationNutritional Effects On BoneOmega-3 Fatty Acid IntakeOmega-3 Fatty Acid Metabolism
Seven-week old female rats fed restricted foods including the fish oils Docosahesaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) and perilla oil with food intake decreased by 50%, had increases of fracture force and bone mineral density (BMD) and decreases in levels of Deoxypiridinoline (Dpd) and Calcium (Ca) in the urine, compared with those of rats with osteoporosis due to restricted soy bean oil food intake. Therefore, the fish oils DHA and EPA and perilla oil depressed excretion of urinary Ca and inhibited osteoporosis due to restricted food intake.
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