Dysregulation of BMI1 and microRNA-16 collaborate to enhance an anti-apoptotic potential in the side population of refractory mantle cell lymphoma

<i>miR-15</i> and <i>miR-16</i> induce apoptosis by targeting BCL2

Amelia Cimmino, George A. Calin, Muller Fabbri et al. · Proceedings of the National Academy of Sciences · 2005 · 3.5K citations · Full text

Hematological Malignancy, Cancer Research, Chronic Lymphocytic Leukemia +15

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Sheng Zhou, John D. Schuetz, Kevin D. Bunting et al. · Nature Medicine · 2001 · 2.3K citations

Developmental Biology, Abc Transporter Bcrp1/abcg2, Medicine +7

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Jacqueline J.L. Jacobs, Karin Kieboom, Silvia Marino et al. · Nature · 1999 · 1.6K citations

Cell Regulation, Cell Division, Genetics +8

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

Julie Lessard, Guy Sauvageau · Nature · 2003 · 1.5K citations

Developmental Biology, Medicine, Stem Cell Mobilization +8

NOD/SCID/γcnull mouse: an excellent recipient mouse model for engraftment of human cells

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