Experimental Biology and Medicine · 1948 · 32 citations · 0 references
Food ChemistryNutritionProtein ChemistryHealth SciencesBiochemistryCrude Trypsin InhibitorMedicineBioanalysisPhysiologyTrypsin InhibitorAlternative Protein SourceProtein PurificationIngestionMetabolismPharmacologyFood SafetyRaw SoybeansActive Trypsin Inhibitor
The addition of an extract of raw soybeans containing active trypsin inhibitor to an enzymatic protein digest (Protolysate) caused a decrease in growth rate and protein utilization. Autoclaving, which inactivated the trypsin inhibitor, abolished the harmful effects of the extract. It has been concluded that the deleterious effects resulting from the ingestion of an extract of raw soybeans are not necessarily due to an interference with the intestinal digestion of dietary protein.