Concepedia

Injection Solvent Enhancement of Peak Height in Reversed-Phase Liquid Chromatography

Norman E. Hoffman, Jonathan H. Y. Chang

Journal of Liquid Chromatography · 1991 · 10 citations · 13 references

DOI

Concepts

Abstract

Abstract Peak height and plate number were Increased under certain conditions when eluites that were dissolved in weak solvents were injected into strong mobile phases. Eluites with a k' of about 3 or greater did not exhibit this phenomenon.

References

13

Liquid chromatographic artifacts and peak distortion: sample-solvent interactions in the separation of carotenoids

Frederick Khachik, Gary R. Beecher, Joseph T. Vanderslice et al. · Analytical Chemistry · 1988 · 69 citations

, , +15

Injection of eluites in solvents stronger than the mobile phase in reversed-phase liquid chromatography

Norman E. Hoffman, Shian-Ling Pan, Abu M. Rustum · Journal of Chromatography A · 1989 · 57 citations

, , +10

Influence of injection solvent on the reversed-phase chromatography of triglycerides

María Z. Tsimidou, Robert Macrae · Journal of Chromatography A · 1984 · 40 citations

, , +13

Effect of a Change in Solvent on Chromatographic Peak Shapes

P. K. Tseng, L. B. Rogers · Journal of Chromatographic Science · 1978 · 33 citations

, , +9

Peak-splitting in reversed-phase, ion-pair high-performance liquid chromatography of sympathomimetic drugs and its probable mechanism

Gary Low, A. M. Duffield, Paul R. Haddad · Chromatographia · 1982 · 30 citations

, , +16