Concepedia

Role for RhoB and PRK in the suppression of epithelial cell transformation by farnesyltransferase inhibitors

Ping-Yao Zeng, Neena S. Rane, Wei Du, Janaki Chintapalli, George C. Prendergast

Oncogene · 2003 · 39 citations · 31 references

DOI

Concepts

References

31

K- and N-Ras Are Geranylgeranylated in Cells Treated with Farnesyl Protein Transferase Inhibitors

David B. Whyte, Paul T. Kirschmeier, Tish Hockenberry et al. · Journal of Biological Chemistry · 1997 · 881 citations · Full text

, , +16

Activation of Rac1, RhoA, and Mitogen-Activated Protein Kinases Is Required for Ras Transformation

Roya Khosravi‐Far, Patricia A. Solski, Geoffrey Clark et al. · Molecular and Cellular Biology · 1995 · 676 citations · Full text

, , +17

Selective Inhibition of <i>ras</i> -Dependent Transformation by a Farnesyltransferase Inhibitor

Nancy E. Kohl, Scott D. Mosser, S. J. DESOLMS et al. · Science · 1993 · 582 citations

, , +13

Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

Nancy E. Kohl, Charles A. Omer, Michael W. Conner et al. · Nature Medicine · 1995 · 539 citations

, , +11

A role for Rho in Ras transformation.

Rongyan Qiu, Jianfei Chen, Frank McCormick et al. · Proceedings of the National Academy of Sciences · 1995 · 534 citations

, , +17