Cholesterol-regulated Translocation of NPC1L1 to the Cell Surface Facilitates Free Cholesterol Uptake

Liqing Yu, Shantaram Bharadwaj, J. Mark Brown, +7

Journal of Biological Chemistry

Lipid MovementCellular PhysiologyCellular Cholesterol UptakeCholesterol UptakeEndocytic Pathway +15

Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma

Kai Ge, James B. DuHadaway, Wei Du, +3

Proceedings of the National Academy of Sciences

Bin1 IsoformsExon 12AAberrant SplicingMedicineTissue-specific Exon +9

RhoB Alteration Is Necessary for Apoptotic and Antineoplastic Responses to Farnesyltransferase Inhibitors

Ai–xue Liu, Wei Du, Jeh-Ping Liu, +2

Molecular and Cellular Biology

Increased expression of PD-L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity

Chaoqi Liu, Jiao Lü, Huiqun Tian, +5

Molecular Medicine Reports

ImmunologyImmune RegulationPathologyCell DeathHuman Papillomavirus 16 +17

Bin1 functionally interacts with Myc and inhibits cell proliferation via multiple mechanisms

Katherine J. Elliott, Daitoku Sakamuro, Amithaba Basu, +8

Oncogene

Cell RegulationMultiple MechanismsImmunologyTumor SuppressorMedicine +3

The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program

Katherine J. Elliott, Kai Ge, Wei Du, +1

Oncogene

Signal TransductionSignaling PathwayCell RegulationApoptosisImmunology +5

Activation of the PI3'K-AKT pathway masks the proapoptotic effects of farnesyltransferase inhibitors.

Wei Du, Aixue Liu, George C. Prendergast

PubMed

ApoptosisCell DeathPathologyMolecular PharmacologySignaling Pathway +18

Prenylation of RhoB Is Required for Its Cell Transforming Function but Not Its Ability to Activate Serum Response Element-dependent Transcription

Peter F. Lebowitz, Wei Du, George C. Prendergast

Journal of Biological Chemistry

ABCB6 Mutations Cause Ocular Coloboma

Lejing Wang, Fei He, Juan Bu, +20

The American Journal of Human Genetics

Ocular DiseaseOphthalmologyMedicinePathogenesisSurgical Pathology +3

Aiolos Promotes Anchorage Independence by Silencing p66Shc Transcription in Cancer Cells

Xichuan Li, Xu Zhao, Wei Du, +16

Cancer Cell

Signaling PathwayCell RegulationMedicineGene ExpressionCancer Cell Biology +8