Distinct roles of different forms of vitamin <scp>E</scp> in <scp>DHA</scp>‐induced apoptosis in triple‐negative breast cancer cells

Abstract

Data, for the first time, demonstrate that DHA induces apoptosis in TNBC cells via activation of ERS/CHOP/DR5-mediated caspase-8 and -9 dependent pro-apoptotic events, and that different forms of vitamin E exhibit distinct effects on DHA-induced apoptosis; namely, inhibition by αT and enhancement by γT3.