SIRT1 Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the Oxidative Stress and p38MAPK Pathways - Concepedia

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SIRT1 Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the Oxidative Stress and p38MAPK Pathways

DOI Full Paper Access

119

Citations

14

References

2015

Year

Yang Ruan, Chunlin Dong, J. Patel, Chao Duan, Xinyue Wang, Xi Wu, Yuan Cao, Lianmei Pu, Dan Lu, Tao Shen,

Cellular Physiology and Biochemistry

Abstract

These results support the role of SIRT1 as an important regulator of cardiomyocyte apoptosis during doxorubicin-induced heart injury, which may represent a potential therapeutic target for doxorubicin-induced cardiomyopathy.

References

	Year	Citations

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