Obesity-associated variants within FTO form long-range functional connections with IRX3

Scott Smemo, Juan J. Tena, Kyoung-Han Kim, +22

Nature

ObesityMetabolic SyndromeEnergy HomeostasisSignal TransductionMolecular Physiology +10

A Fine-Scale Chimpanzee Genetic Map from Population Sequencing

Adam Auton, Adi Fledel-Alon, Susanne P. Pfeifer, +20

Science

BiologyMolecular EcologyBase CompositionMedicineGenetics +12

An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a <i>MYC</i> enhancer

Nora Wasserman, Ivy Aneas, Marcelo A. Nóbrega

Genome Research

Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders

Carlos Gómez-Marín, Juan J. Tena, Rafael D. Acemel, +11

Proceedings of the National Academy of Sciences

A promoter interaction map for cardiovascular disease genetics

Lindsey E. Montefiori, Débora R. Sobreira, Noboru J. Sakabe, +7

eLife

Promoter Interaction MapGeneticsGenetic EpidemiologyGene CharacterizationGene Expression Profiling +16

HIF1α Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes

Nuno Guimarães‐Camboa, Jennifer Stowe, Ivy Aneas, +10

Developmental Cell

Transcriptional RegulationRedox RegulatorPhysiologyHypoxia (Medicine)Medicine +5

Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal

Margaret G. Distler, Leigh D. Plant, Greta Sokoloff, +7

Journal of Clinical Investigation

Molecular PharmacologyStress HormonePsychiatryGabaa Receptor ActivationMedicine +13

Alterations in <i>TCF7L2</i> expression define its role as a key regulator of glucose metabolism

Daniel Savic, Honggang Ye, Ivy Aneas, +3

Genome Research

GeneticsGenetic EpidemiologyMetabolic RemodelingGlucose ToleranceInsulin Signaling +24

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome

Anamaria A. Camargo, Helena P. B. Samaia, Emmanuel Dias‐Neto, +96

Proceedings of the National Academy of Sciences

Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function

Tao Shen, Ivy Aneas, Noboru J. Sakabe, +13

Journal of Clinical Investigation

Cardiac MuscleGeneticsCardiac Progenitor CellsMolecular GeneticsCell Regulation +15