<i>FTO</i> Obesity Variant Circuitry and Adipocyte Browning in Humans

Melina Claussnitzer, Simon N. Dankel, Kyoung-Han Kim, +16

New England Journal of Medicine

Obesity-associated variants within FTO form long-range functional connections with IRX3

Scott Smemo, Juan J. Tena, Kyoung-Han Kim, +22

Nature

ObesityMetabolic SyndromeEnergy HomeostasisSignal TransductionMolecular Physiology +10

The Homeodomain Transcription Factor Irx5 Establishes the Mouse Cardiac Ventricular Repolarization Gradient

Danny L. Costantini, Eric Arruda, Pooja Agarwal, +19

Cell

Cardiac MuscleTranscriptional RegulationMolecular PhysiologySignal TransductionPhysiology +7

MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1L613V mutation

Xue Wu, Jeremy A. Simpson, Jenny H. Hong, +5

Journal of Clinical Investigation

Cardiac MuscleHeart FailureGeneticsSudden DeathPathology +18

Glucagon-Like Peptide (GLP)-1(9-36)Amide-Mediated Cytoprotection Is Blocked by Exendin(9-39) Yet Does Not Require the Known GLP-1 Receptor

Kiwon Ban, Kyoung-Han Kim, Chan-Kyung Cho, +5

Endocrinology

Intermittent fasting promotes adipose thermogenesis and metabolic homeostasis via VEGF-mediated alternative activation of macrophage

Kyoung-Han Kim, Yun Hye Kim, Joe Eun Son, +17

Cell Research

PI3Kγ is required for NMDA receptor–dependent long-term depression and behavioral flexibility

Jae‐Ick Kim, Hye‐Ryeon Lee, Su-Eon Sim, +20

Nature Neuroscience

PsychiatryMood SymptomMedicinePsychopharmacologyDepression +8

<i>Iroquois homeobox gene 3</i> establishes fast conduction in the cardiac His–Purkinje network

Shanshan Zhang, Kyoung-Han Kim, Anna Rosén, +23

Proceedings of the National Academy of Sciences

Cardiac MuscleGene 3Cellular PhysiologyTranscriptional RegulationSignaling Pathway +20

Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis

Shaza Asif, Ri Youn Kim, Thet Fatica, +8

Molecular Metabolism

Metabolic SyndromeBiochemistryHmgcs2-mediated KetogenesisLiver PhysiologyCell Death +8

Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches

Ji‐Eun Kim, Lijiang Fei, Wen-Chi Yin, +12

Nature Communications

GeneticsGastroenterologyCellular PhysiologyTissue DevelopmentSignaling Pathway +20