Huntington's Disease Intranuclear Inclusions Contain Truncated, Ubiquitinated Huntingtin Protein

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

Life Sciences, Neurobiology, Neuroscience +16

Neuropathological Classification of Huntingtonʼs Disease

Jean‐Paul Vonsattel, Richard H. Myers, Thomas J. Stevens et al. · Journal of Neuropathology & Experimental Neurology · 1985 · 2.6K citations

Medicine, Neurology, Neuroscience +17

Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

Life Sciences, Genetics, Neurology +17

Huntingtin-Encoded Polyglutamine Expansions Form Amyloid-like Protein Aggregates In Vitro and In Vivo

Eberhard Scherzinger, Rudi Lurz, Mark Turmaine et al. · Cell · 1997 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +10

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

Susan E. Andrew, Y. Paul Goldberg, Berry Kremer et al. · Nature Genetics · 1993 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +12