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Synthesis and evaluation of 6-methylene-bridged uracil derivatives. Part 2: Optimization of inhibitors of human thymidine phosphorylase and their selectivity with uridine phosphorylase

Medicinal ChemistryDerivative (Chemistry)BiochemistryNatural SciencesMedicineHuman Thymidine PhosphorylaseOrganic ChemistryChemical BiologyPharmacologyPharmaceutical ChemistryDrug Discovery6-Methylene-bridged Uracil DerivativesUridine Phosphorylase