Tomohiro Emura

Structure and activity of specific inhibitors of thymidine phosphorylase to potentiate the function of antitumor 2′-deoxyribonucleosides

Masakazu Fukushima, Norihiko Suzuki, Tomohiro Emura et al. · Biochemical Pharmacology · 2000 · 236 citations

Specific Inhibitors, Medicinal Chemistry, Antitumor 2′-Deoxyribonucleosides +7

A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA

Tomohiro Emura, Norihiko Suzuki, Masahiro Yamaguchi et al. · International Journal of Oncology · 2004 · 119 citations

Antitumor Activity, Molecular Biology, Pathology +20

A novel antimetabolite, TAS-102 retains its effect on FU-related resistant cancer cells

Tomohiro Emura, Yuko Murakami, Fumio Nakagawa et al. · International Journal of Molecular Medicine · 2004 · 105 citations

Pathology, Cancer Biology, Liver Metastasis +17

Different mechanisms of acquired resistance to fluorinated pyrimidines in human colorectal cancer cells.

Yuko Murakami, Hideki Kazuno, Tomohiro Emura et al. · International Journal of Oncology · 2000 · 99 citations

Tumor Biology, Different Mechanisms, Oncology +13

An optimal dosing schedule for a novel combination antimetabolite, TAS-102, based on its intracellular metabolism and its incorporation into DNA

Tomohiro Emura, Fumio Nakagawa, Akio Fujioka et al. · International Journal of Molecular Medicine · 2004 · 85 citations

Pharmaceutical Science, Chemical Biology, Culture Medium +21