Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll‐like receptor 4 - Concepedia

Concepedia

Publication | Closed Access

Alarmins S100A8 and S100A9 elicit a catabolic effect in human osteoarthritic chondrocytes that is dependent on Toll‐like receptor 4

191

Citations

32

References

2011

Year

R. Schelbergen, Arjen B. Blom, Martijn H. J. van den Bosch, A. Sloëtjes, Shahla Abdollahi‐Roodsaz, B Willem Schreurs, John S. Mort, Thomas Vogl, Johannes Roth, Wim B. van den Berg,

Arthritis & Rheumatism

Abstract

S100A8 and S100A9 have a catabolic effect on human chondrocytes that is TLR-4 dependent. OA chondrocytes are more sensitive than normal chondrocytes to S100 stimulation.

References

	Year	Citations

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