Thasia Woodworth

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

Josef S Smolen, André Beaulieu, Andrea Rubbert‐Roth et al. · The Lancet · 2008 · 1.4K citations

Inflammation, Rheumatology, Rheumatoid Disorder +10

Interleukin‐6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease‐modifying antirheumatic drugs: The tocilizumab in combination with traditional disease‐modifying antirheumatic drug therapy study

Mark C. Genovese, James D. McKay, Eduardo Mysler et al. · Arthritis & Rheumatism · 2008 · 853 citations

Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study

Graeme Jones, Anthony Sebba, Jianhui Gu et al. · Annals of the Rheumatic Diseases · 2009 · 789 citations · Full text

Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

Paul S. Changelian, Mark E. Flanagan, Douglas J. Ball et al. · Science · 2003 · 667 citations · Full text

Immunology, Cell Death, Immunotherapy +21

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

Scott Gottlieb, Patricia Gilleaudeau, Ray A. Johnson et al. · Nature Medicine · 1995 · 613 citations

Inflammation, Pathogenic Basis, Autoimmune Disease +11