André Beaulieu

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

Josef S Smolen, André Beaulieu, Andrea Rubbert‐Roth et al. · The Lancet · 2008 · 1.4K citations

Medicine, Immunology, Pharmacology +16

Brodalumab, an Anti-IL17RA Monoclonal Antibody, in Psoriatic Arthritis

Philip J. Mease, Mark C. Genovese, Maria Greenwald et al. · New England Journal of Medicine · 2014 · 392 citations · Full text

Medicine, Immunology, Pharmacotherapy +16

Comparison of the effect of rofecoxib (a cyclooxygenase 2 inhibitor), ibuprofen, and placebo on the gastroduodenal mucosa of patients with osteoarthritis: A randomized, double-blind, placebo-controlled trial

Christopher J. Hawkey, Loren Laine, Thomas Simon et al. · Arthritis & Rheumatism · 2000 · 365 citations

Medicine, Pharmacology, Pharmacotherapy +13

Effect of interleukin-6 receptor blockade on surrogates of vascular risk in rheumatoid arthritis: MEASURE, a randomised, placebo-controlled study

Iain B. McInnes, Liz Thompson, Jon T. Giles et al. · Annals of the Rheumatic Diseases · 2013 · 329 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Adalimumab significantly reduces both spinal and sacroiliac joint inflammation in patients with ankylosing spondylitis: A multicenter, randomized, double‐blind, placebo‐controlled study

R. Lambert, David Salonen, Proton Rahman et al. · Arthritis & Rheumatism · 2007 · 255 citations

Medicine, Neurology, Orthopedic Rehabilitation +14