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BACE-1 inhibitors part 3: Identification of hydroxy ethylamines (HEAs) with nanomolar potency in cells

Paul Beswick, Nicolas Charrier, Brian Clarke, Emmanuel H. Demont, Colin Dingwall, R. Dunsdon, Andrew Faller, Robert J. Gleave, Julie A. Hawkins, Ishrut Hussain,

Bioorganic & Medicinal Chemistry Letters · 2008 · 58 citations · 3 references

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3

Hydrogen bonding. Part 9. Solute proton donor and proton acceptor scales for use in drug design

Michael H. Abraham, Philip P. Duce, David V. Prior et al. · Journal of the Chemical Society Perkin Transactions 2 · 1989 · 234 citations

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Oral administration of a potent and selective non‐peptidic BACE‐1 inhibitor decreases β‐cleavage of amyloid precursor protein and amyloid‐β production <i>in vivo</i>

Ishrut Hussain, Julie A. Hawkins, David C. Harrison et al. · Journal of Neurochemistry · 2006 · 198 citations · Full text

, , +14

Stereoselective synthesis of 3-heteroaromatic-substituted alanines

Piero Dalla Croce, Concetta La Rosa, Enrica Pizzatti · Tetrahedron Asymmetry · 2000 · 22 citations

, , +8