Differential effects of IFN-α on the expression of various TH2 cytokines in human CD4+ T cells

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Jason D. Fontenot, Marc A. Gavin, Alexander Y. Rudensky · Nature Immunology · 2003 · 7.6K citations

Lymphocyte Development, T-regulatory Cell, Immunology +9

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

Genetics, Genomic Mechanism, Gene Regulation +5

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Wei-ping Zheng, Richard A. Flavell · Cell · 1997 · 2.3K citations · Full text

IL-4 directs the development of Th2-like helper effectors.

Susan L. Swain, Andrew D. Weinberg, M English et al. · The Journal of Immunology · 1990 · 1.3K citations · Full text

Lymphocyte Development, Immunology, Immune Regulation +17

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice.

Robert A. Seder, W E Paul, Mark M. Davis et al. · The Journal of Experimental Medicine · 1992 · 1K citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +19