Concepedia

CD248 and its cytoplasmic domain: A therapeutic target for arthritis

Margarida Maia, Astrid De Vriese, Tom Janssens, Michaël Moons, Kristel Van Landuyt, Jan Tavernier, Rik Lories, Edward M. Conway

Arthritis & Rheumatism · 2010 · 77 citations · 40 references

DOI

Abstract

CD248 contributes to synovial hyperplasia and leukocyte accumulation in inflammatory arthritis, the effects of which are mediated partly via its cytoplasmic domain. CD248 is therefore a potential new target in the treatment of arthritis.

References

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