MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

Angelika Bonauer, Guillaume Carmona, Masayoshi Iwasaki, +13

Science

Endothelial CellsImmunologyMicrorna-92a Controls AngiogenesisLimb IschemiaAngiogenesis +19

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1

Aernout Luttun, Marc Tjwa, Lieve Moons, +19

Nature Medicine

AngiogenesisPlgf TreatmentVascular AdaptationVascular SurgeryIschemic Tissues +10

Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Veerle Compernolle, Koen Brusselmans, Till Acker, +14

Nature Medicine

Acute Lung InjuryDevelopmental BiologyLung InflammationRespiratory Distress Syndrome (Pulmonary Critical Care)Physiology +10

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism

Julián Aragonés, Martin Schneider, Katie Van Geyte, +43

Nature Genetics

BiochemistryRedox RegulatorPhysiologyHypoxia ToleranceHypoxia (Medicine) +7

Heterozygous deficiency of hypoxia-inducible factor–2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

Koen Brusselmans, Veerle Compernolle, Marc Tjwa, +4

Journal of Clinical Investigation

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

Kirsten De Ridder, Alexandra Sevko, Janina Heide, +10

OncoImmunology

Fibrinogen drives dystrophic muscle fibrosis via a TGFβ/alternative macrophage activation pathway

Berta Vidal, Antonio L. Serrano, Marc Tjwa, +14

Genes & Development

Cardiomyocyte-Specific Overexpression of Nitric Oxide Synthase 3 Improves Left Ventricular Performance and Reduces Compensatory Hypertrophy After Myocardial Infarction

Stefan Janssens, Péter Pokreisz, Luc Schoonjans, +11

Circulation Research

Increased skeletal VEGF enhances β‐catenin activity and results in excessively ossified bones

Christa Maes, Steven Goossens, Sonia Bartunkova, +17

The EMBO Journal

Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin

David Kaluza, Sabine Gesierich, Tso-Pang Yao, +9

The EMBO Journal

Endothelial Cell PathobiologyAngiogenesisClass Iib Hdac6Cell SignalingEndothelial Cell Migration +7