Koen Brusselmans

Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

Peter Carmeliet, Yuval Dor, Jean-Marc Herbert et al. · Nature · 1998 · 2.5K citations

Tumor Biology, Hypoxia-mediated Apoptosis, Redox Regulator +15

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

Bert Oosthuyse, Lieve Moons, Erik Storkebaum et al. · Nature Genetics · 2001 · 1K citations

Neurodegenerative Diseases, Motor Neuron Degeneration, Hypoxia-response Element +10

Loss of HIF-2α and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

Veerle Compernolle, Koen Brusselmans, Till Acker et al. · Nature Medicine · 2002 · 727 citations

Acute Lung Injury, Developmental Biology, Lung Inflammation +12

<i>De novo</i> Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

Evelien Rysman, Koen Brusselmans, Katryn Scheys et al. · Cancer Research · 2010 · 694 citations · Full text

Lipid Peroxidation, Lipid Movement, Cancer Biology +16

Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188

Peter Carmeliet, Yin‐Shan Ng, Dieter Nuyens et al. · Nature Medicine · 1999 · 681 citations

Cardiomyopathy, Heart Failure, Angiogenesis +12