Microtubule-stabilizing agent prevents protein accumulation-induced loss of synaptic markers

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

Robert D. Terry, Eliezer Masliah, David P. Salmon et al. · Annals of Neurology · 1991 · 4.3K citations

Promotion of microtubule assembly in vitro by taxol

Peter B. Schiff, Jane Fant, Susan Band Horwitz · Nature · 1979 · 3.6K citations

Micropropagation, Cell Culture, Cytoskeleton +4

Learning Induces Long-Term Potentiation in the Hippocampus

Jonathan R. Whitlock, Arnold J. Heynen, Marshall G. Hussain Shuler et al. · Science · 2006 · 1.9K citations

Synaptic Transmission, Neurotransmission, Social Sciences +17

Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease

Gorazd B. Stokin, Concepción Lillo, Tomás L. Falzone et al. · Science · 2005 · 1.2K citations

Axonal Defects, Neurochemical Biomarkers, Cytoskeleton +20

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules

A C Alonso, Inge Grundke‐Iqbal, Khalid Iqbal · Nature Medicine · 1996 · 843 citations

Alzheimer's Disease, Protein Folding, Molecular Biology +8