Concepedia

Synaptic Protein Aggregation

Synaptic Protein Aggregation is a pathological process in which misfolded or dysfunctional proteins accumulate abnormally at synaptic sites, disrupting synaptic structure and function through the formation of toxic aggregates that impair neuronal communication.

153

Publications

14.9K

Citations

990

Authors

333

Institutions

Publications per year

2017–2026

51

Parents

Publications

153

Dopaminergic Loss and Inclusion Body Formation in α-Synuclein Mice: Implications for Neurodegenerative Disorders

Eliezer Masliah, Edward Rockenstein, Isaac Veinbergs et al. · Science · 2000 · 1.8K citations

, , +17

Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

Laura A. Volpicelli‐Daley, Kelvin C. Luk, Tapan P. Patel et al. · Neuron · 2011 · 1.6K citations · Full text

, , +14

Dementia with Lewy bodies.

Ian G. McKeith · PubMed · 2004 · 760 citations

, , +17

Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in α-Synuclein Models of Parkinson's and Lewy Body Diseases

Brian Spencer, Rewati Potkar, Margarita Trejo et al. · Journal of Neuroscience · 2009 · 582 citations · Full text

, , +17

The Synaptic Accumulation of Hyperphosphorylated Tau Oligomers in Alzheimer Disease Is Associated With Dysfunction of the Ubiquitin-Proteasome System

Hwan‐Ching Tai, Alberto Serrano‐Pozo, Tadafumi Hashimoto et al. · American Journal Of Pathology · 2012 · 459 citations · Full text

, , +17

1–5 of 153

Authors

990

  1. EM
    Eliezer Masliah

    University of California San Diego, United States

    9 publications · 3.2K citations

    9

    h-index

  2. IF
    Isidró Ferrer

    Universitat de Barcelona, Spain

    4 publications · 200 citations

    4

    h-index

  3. MM
    Margaret Mallory

    University of California San Diego, United States

    4 publications · 2.1K citations

    4

    h-index

  4. CB
    Clive Bate

    Royal Veterinary College, United Kingdom

    4 publications · 214 citations

    4

    h-index

  5. AW
    Alun Williams

    University of Cambridge, United Kingdom

    4 publications · 214 citations

    4

    h-index

1–5 of 990

Institutions

333

  1. University of California San Diego

    San Diego, United States

    12 h-index

    51 publications

    17.1K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    40 publications

    2.2K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    22 publications

    885 citations

  4. Inserm

    Paris, France

    6 h-index

    24 publications

    1.2K citations

  5. Harvard University

    Cambridge, United States

    5 h-index

    14 publications

    4K citations

  6. Universitat de Barcelona

    Barcelona, Spain

    5 h-index

    10 publications

    652 citations

  7. Sanford Burnham Prebys Medical Discovery Institute

    La Jolla, United States

    4 h-index

    9 publications

    732 citations

  8. University of Kentucky

    Lexington, United States

    4 h-index

    9 publications

    869 citations

1–8 of 333

Venues

  1. Journal of Neuroscience

    10 publications · 2K citations

    10

    h-index

  2. Neurobiology of Aging

    7 publications · 519 citations

    7

    h-index

  3. PLoS ONE

    6 publications · 307 citations

    6

    h-index

  4. Journal of Alzheimer s Disease

    JAD · 5 publications · 521 citations

    5

    h-index

  5. Acta Neuropathologica

    5 publications · 683 citations

    5

    h-index

1–5