Evaluation of the Effect of Syringe Surfaces on Protein Formulations

Overlooking Subvisible Particles in Therapeutic Protein Products: Gaps That May Compromise Product Quality

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2008 · 578 citations · Full text

Protein Chemistry, Biochemistry, Subvisible Particles +10

Silicone Oil- and Agitation-Induced Aggregation of a Monoclonal Antibody in Aqueous Solution

Renuka Thirumangalathu, Sampathkumar Krishnan, Margaret Speed Ricci et al. · Journal of Pharmaceutical Sciences · 2009 · 287 citations · Full text

Immunocytochemical Technique, Engineering, Aqueous Solution +13

Silicone Oil Induced Aggregation of Proteins

LaToya S. Jones, Allyn M. Kaufmann, C. Russell Middaugh · Journal of Pharmaceutical Sciences · 2005 · 276 citations

Microemulsion, Protein Engineering, Protein Phase Separation +2

The increased incidence of pure red cell aplasia with an Eprex formulation in uncoated rubber stopper syringes

Katia Boven, Scott Stryker, John Knight et al. · Kidney International · 2005 · 245 citations · Full text

Tissue Engineering, Cell Aplasia, Engineering +7

Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: Essential need to use orthogonal methods to assure the quality of therapeutic protein products

John F. Carpenter, Theodore W. Randolph, Wim Jiskoot et al. · Journal of Pharmaceutical Sciences · 2009 · 202 citations

Potential Inaccurate Quantitation, Orthogonal Methods, Protein Aggregates +16