Concepedia

Simultaneous knockdown of the expression of two genes using multiple shRNAs and subsequent knock-in of their expression

Xueming Xu, Min‐Hyuk Yoo, Bradley A. Carlson, Vadim N. Gladyshev, Dolph L. Hatfield

Nature Protocols · 2009 · 33 citations · 44 references

DOIFull text

Open access

Concepts

References

44

A "Silent" Polymorphism in the <i>MDR</i> 1 Gene Changes Substrate Specificity

Chava Kimchi‐Sarfaty, Jung Mi Oh, In‐Wha Kim et al. · Science · 2006 · 2.5K citations · Full text

, , +15

Rational siRNA design for RNA interference

Angela Reynolds, Devin Leake, Queta Boese et al. · Nature Biotechnology · 2004 · 2.1K citations

, , +12

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

Dirk Grimm, Konrad L. Streetz, Catherine L. Jopling et al. · Nature · 2006 · 1.7K citations

, , +8

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

Sayda M. Elbashir · The EMBO Journal · 2001 · 1.5K citations · Full text

, , +12

3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets

Amanda Birmingham, Emily M. Anderson, Angela Reynolds et al. · Nature Methods · 2006 · 907 citations

, , +14