Concepedia

ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21WAF1

Jikhyon Han, Kim Yl, N-G Her, T-K Ha, Sehyoun Yoon, S-I Jeong, Min Ju Kang, B-K Ryu, S-G Chi

Cell Death and Differentiation · 2013 · 71 citations · 36 references

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36

p21 is necessary for the p53-mediated G1 arrest in human cancer cells.

Todd Waldman, K. W. Kinzler, Bert Vogelstein · PubMed · 1995 · 1.2K citations

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Differential Roles for Cyclin-Dependent Kinase Inhibitors p21 and p16 in the Mechanisms of Senescence and Differentiation in Human Fibroblasts

Gretchen H. Stein, Linda F. Drullinger, Alexandre Soulard et al. · Molecular and Cellular Biology · 1999 · 849 citations · Full text

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Integration of interferon-α/β signalling to p53 responses in tumour suppression and antiviral defence

Akinori Takaoka, Sumio Hayakawa, Hideyuki Yanai et al. · Nature · 2003 · 846 citations

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A Novel Role for High-Mobility Group A Proteins in Cellular Senescence and Heterochromatin Formation

Masashi Narita, Masako Narita, Valery Krizhanovsky et al. · Cell · 2006 · 617 citations · Full text

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Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

Peter Liston, Wai Gin Fong, N. Lynn Kelly et al. · Nature Cell Biology · 2001 · 438 citations

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