K. W. Kinzler

APC mutations occur early during colorectal tumorigenesis

Steven M. Powell, Nathan Zilz, Yasmin Beazer-Barclay et al. · Nature · 1992 · 1.9K citations

Somatic Variant, Apc Mutations, Medicine +6

p21 is necessary for the p53-mediated G1 arrest in human cancer cells.

Todd Waldman, K. W. Kinzler, Bert Vogelstein · PubMed · 1995 · 1.2K citations

Cell Death, Pathology, P53-dependent G1 Arrest +16

PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs

Tong‐Chuan He, Timothy A. Chan, B Vogelstein et al. · Cell · 1999 · 1.1K citations · Full text

Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC

Steven J. Laken, Gloria M. Petersen, Stephen B. Gruber et al. · Nature Genetics · 1997 · 687 citations

Hypermutable Tract, Gastrointestinal Oncology, Medicine +8

p53 Mutation and MDM2 amplification in human soft tissue sarcomas.

Fredrick S. Leach, Takashi Tokino, Paul S. Meltzer et al. · PubMed · 1993 · 538 citations

Pathology, Cancer Biology, Tumor Biology +16