Generation and Accumulation of Immunosuppressive Adenosine by Human CD4+CD25highFOXP3+ Regulatory T Cells

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Tyler J. Curiel, George Coukos, Linhua Zou et al. · Nature Medicine · 2004 · 5K citations

Cancer Immunosurveillance, Specific Recruitment, T-regulatory Cell +9

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Hervé Groux, Anne O’Garra, Mike Bigler et al. · Nature · 1997 · 3.6K citations

Inflammation, Mucosal Immunology, T-regulatory Cell +8

Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

Silvia Deaglio, Karen M. Dwyer, Wenda Gao et al. · The Journal of Experimental Medicine · 2007 · 2.3K citations · Full text

The inhibitory cytokine IL-35 contributes to regulatory T-cell function

Lauren W. Collison, Creg J. Workman, Timothy Kuo et al. · Nature · 2007 · 2K citations

Inflammation, Autoimmune Disease, Inhibitory Cytokine Il-35 +7

Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage

Akio Ohta, Michail V. Sitkovsky · Nature · 2001 · 1.3K citations

Inflammation, Anti-inflammatory, Signal Transduction +14