Concepedia

Adult mouse astrocytes degrade amyloid-β in vitro and in situ

Tony Wyss‐Coray, John D. Loike, Thomas C. Brionne, Emily Ming‐Chieh Lu, Roman Anankov, Fengrong Yan, Samuel C. Silverstein, Jens Husemann

Nature Medicine · 2003 · 898 citations · 22 references

DOI

Concepts

References

22

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard, Catherine Cannon, Robin Barbour et al. · Nature Medicine · 2000 · 2K citations

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High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience · 2000 · 1.9K citations · Full text

, , +17

Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger Receptor

Donata M. Paresce, Richik N. Ghosh, Frederick R. Maxfield · Neuron · 1996 · 669 citations · Full text

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TGF-β1 promotes microglial amyloid-β clearance and reduces plaque burden in transgenic mice

Tony Wyss‐Coray, Carol Lin, Fengrong Yan et al. · Nature Medicine · 2001 · 596 citations

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CD36, a Class B Scavenger Receptor, Is Expressed on Microglia in Alzheimer's Disease Brains and Can Mediate Production of Reactive Oxygen Species in Response to β-Amyloid Fibrils

Indra Sethy Coraci, Jens Husemann, Joan W. Berman et al. · American Journal Of Pathology · 2002 · 392 citations · Full text

, , +17