Concepedia

Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors

Suvi Rajamäki, Anna Innitzer, Chiara Falciani, Cristina Tintori, Frauke Christ, Myriam Witvrouw, Zeger Debyser, Silvio Massa, Maurizio Botta

Bioorganic & Medicinal Chemistry Letters · 2009 · 70 citations · 9 references

DOIFull text

Open access

Concepts

References

9

Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells

Daria J. Hazuda, Peter J. Felock, Marc Witmer et al. · Science · 2000 · 1.1K citations

, , +16

Discovery of Raltegravir, a Potent, Selective Orally Bioavailable HIV-Integrase Inhibitor for the Treatment of HIV-AIDS Infection

Vincenzo Summa, Alessia Petrocchi, Fabio Bonelli et al. · Journal of Medicinal Chemistry · 2008 · 634 citations · Full text

, , +17

Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity

Paul C. Unangst, David T. Connor, Wiaczeslaw A. Cetenko et al. · Journal of Medicinal Chemistry · 1994 · 163 citations · Full text

, , +13

Regioselective Palladium-Catalyzed Arylation of 2-Furaldehyde

Michael S. McClure, Bobby Glover, Ellen McSorley et al. · Organic Letters · 2001 · 161 citations

, , +17

Reaction of Rosmarinic Acid with Nitrite Ions in Acidic Conditions: Discovery of Nitro- and Dinitrorosmarinic Acids as New Anti-HIV-1 Agents

Mélanie Dubois, Fabrice Bailly, Gladys Mbemba et al. · Journal of Medicinal Chemistry · 2008 · 80 citations · Full text

, , +16