Concepedia

New inhibitors of the complement system inspired in K76-COOH. A SAR study of filifolinol derivatives through modifications of the C3′ position

Enrique L. Larghi, María A. Operto, René Torres, Teodoro S. Kaufman

Bioorganic & Medicinal Chemistry Letters · 2009 · 14 citations · 38 references

DOI

Concepts

References

38

Soluble Human Complement Receptor Type 1: In Vivo Inhibitor of Complement Suppressing Post-Ischemic Myocardial Inflammation and Necrosis

Harlan F. Weisman, Michelle K. Leppo, Henry C. Marsh et al. · Science · 1990 · 979 citations

, , +17

Complement in inflammatory tissue damage and disease

Tom Eirik Mollnes, Wen‐Chao Song, John D. Lambris · Trends in Immunology · 2002 · 165 citations

, , +12

A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice

Joshua M. Thurman, Damian Kraus, Guillermina Girardi et al. · Molecular Immunology · 2004 · 161 citations

, , +12

Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection

Kazunori Murata, William M. Baldwin · Transplantation Reviews · 2009 · 132 citations · Full text

, , +16

An Anticomplementary Agent, K-76 Monocarboxylic Acid: Its Site and Mechanism of Inhibition of the Complement Activation Cascade

Kyongsu Hong, Taroh Kinoshita, Wasei Miyazaki et al. · The Journal of Immunology · 1979 · 104 citations

, , +11