Concepedia

PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis

Kiyoshi Hirai, Takeshi Hayashi, Pak H. Chan, Jianying Zeng, Guo‐Yuan Yang, Vladimir J. Basus, Thomas Leroy James, Lawrence Litt

Molecular Brain Research · 2004 · 40 citations · 41 references

DOI

Concepts

References

41

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

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Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Anne Brunet, Azad Bonni, Michael J. Zigmond et al. · Cell · 1999 · 6.6K citations · Full text

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Darren A.E. Cross, Dario R. Alessi, Philip Cohen et al. · Nature · 1995 · 5.2K citations

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Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

Jie Yang, Xuesong Liu, Kapil N. Bhalla et al. · Science · 1997 · 4.9K citations

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